The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNF(Y)) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases

Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor (CNF(Y)), but the functional consequences of this toxin for host-pathogen interactions during the infection are unknown. In the present study we show that CNF(Y) has a strong influence on virulence. We demonstrate...

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Detalhes bibliográficos
Main Authors: Schweer, Janina, Kulkarni, Devesha, Kochut, Annika, Pezoldt, Joern, Pisano, Fabio, Pils, Marina C., Genth, Harald, Huehn, Jochen, Dersch, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820761/
https://ncbi.nlm.nih.gov/pubmed/24244167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003746
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