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Antibody receptors steal the sweet spotlight

Immunoglobulin G (IgG) antibodies function, in part, through ligation of cell-surface Fc receptors such as FcγRIIIA (also known as CD16A). IgG glycosylation is known to impact antibody function, but the role of FcγRIIIA glycans, if any, is unclear. Patel et al. now reveal that these glycans do impac...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Oliva, Kelsey D., Cavanaugh, Jill M., Cobb, Brian A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846142/
https://ncbi.nlm.nih.gov/pubmed/29523693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.001955
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