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Antibody receptors steal the sweet spotlight

Immunoglobulin G (IgG) antibodies function, in part, through ligation of cell-surface Fc receptors such as FcγRIIIA (also known as CD16A). IgG glycosylation is known to impact antibody function, but the role of FcγRIIIA glycans, if any, is unclear. Patel et al. now reveal that these glycans do impac...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Oliva, Kelsey D., Cavanaugh, Jill M., Cobb, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846142/
https://ncbi.nlm.nih.gov/pubmed/29523693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.001955
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