Integrity of glycosylation processing of a glycan-depleted trimeric HIV-1 immunogen targeting key B-cell lineages

Broadly neutralizing antibodies (bNAbs) that target the trimeric HIV-1 envelope glycoprotein spike (Env) are tools that can guide the design of recombinant Env proteins intended to engage the predicted human germline precursors of bNAbs (gl-bNAbs). The protein components of gl-bNAb epitopes are ofte...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Behrens, Anna-Janina, Kumar, Abhinav, Medina-Ramirez, Max, Cupo, Albert, Marshall, Kevin, Portillo, Victor C., Harvey, David J., Ozorowski, Gabriel, Zitzmann, Nicole, Wilson, Ian A., Ward, Andrew B., Struwe, Weston B., Moore, John P., Sanders, Rogier W., Crispin, Max
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846105/
https://ncbi.nlm.nih.gov/pubmed/29420040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00639
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