Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel

BACKGROUND: Colorectal cancer (CRC) screening might be improved by using a measure of prior risk to modulate screening intensity or the faecal immunochemical test threshold. Intermediate molecular biomarkers could aid risk prediction by capturing both known and unknown risk factors. METHODS: We samp...

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Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Fernandez-Rozadilla, Ceres, Kartsonaki, Christiana, Woolley, Connor, McClellan, Michael, Whittington, Deb, Horgan, Gareth, Leedham, Simon, Kriaucionis, Skirmantas, East, James, Tomlinson, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2018
Témata:
Genetics & Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846076/
https://ncbi.nlm.nih.gov/pubmed/29438375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.486
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