Cargando...
Stereochemical Structure Activity Relationship Studies (S-SAR) of Tetrahydrolipstatin
[Image: see text] Tetrahydrolipstatin (THL), its enantiomer, and an additional six diastereomers were evaluated as inhibitors of the hydrolysis of p-nitrophenyl butyrate by porcine pancreatic lipase. IC(50)s were found for all eight stereoisomers ranging from a low of 4.0 nM for THL to a high of 930...
Gardado en:
| Publicado en: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2018
|
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846039/ https://ncbi.nlm.nih.gov/pubmed/29541373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00050 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|