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Cryptocaryol Structure–Activity Relationship Study of Cancer Cell Cytotoxicity and Ability to Stabilize PDCD4
[Image: see text] The synthetic cryptocaryols A and B and a series of their analogues have been evaluated for their cytotoxicity and their ability to stabilize the tumor suppressor PDCD4. Cytotoxicities in the 3 to 30 μM range were found. Both the cytotoxicity and PDCD4 stabilizing ability were tole...
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| Główni autorzy: | , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2014
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4029205/ https://ncbi.nlm.nih.gov/pubmed/24900873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4005039 |
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