Cryptocaryols A–H, α-Pyrone-Containing 1,3-Polyols from Cryptocarya sp. Implicated in Stabilizing the Tumor Suppressor Pdcd4

[Image: see text] A high-throughput cell-based reporter assay designed to identify small-molecule stabilizers of the tumor suppressor Pdcd4 was used to screen extracts in the NCI Natural Products Repository. Bioassay-guided fractionation of an extract from a Papua New Guinea collection of the tropic...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Grkovic, Tanja, Blees, Johanna S., Colburn, Nancy H., Schmid, Tobias, Thomas, Cheryl L., Henrich, Curtis J., McMahon, James B., Gustafson, Kirk R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671369/
https://ncbi.nlm.nih.gov/pubmed/21539301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np100918z
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