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High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors
Integration-deficient lentiviral vectors (IDLVs) are promising gene delivery tools that retain the high transduction efficiency of standard lentiviral vectors, yet fail to integrate as proviruses and are instead converted into episomal circles. These episomes are metabolically stable and support lon...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Publishers
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845930/ https://ncbi.nlm.nih.gov/pubmed/29289570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.12.029 |
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