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High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors

Integration-deficient lentiviral vectors (IDLVs) are promising gene delivery tools that retain the high transduction efficiency of standard lentiviral vectors, yet fail to integrate as proviruses and are instead converted into episomal circles. These episomes are metabolically stable and support lon...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Control Release
Prif Awduron: Ahmed, Sherif G., Waddington, Simon N., Boza-Morán, Maria Gabriela, Yáñez-Muñoz, Rafael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Science Publishers 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845930/
https://ncbi.nlm.nih.gov/pubmed/29289570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.12.029
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