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Integration-deficient Lentiviral Vectors: A Slow Coming of Age

Lentiviral vectors are very efficient at transducing dividing and quiescent cells, which makes them highly useful tools for genetic analysis and gene therapy. Traditionally this efficiency was considered dependent on provirus integration in the host cell genome; however, recent results have challeng...

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Bibliographic Details
Main Authors: Wanisch, Klaus, Yáñez-Muñoz, Rafael J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835240/
https://ncbi.nlm.nih.gov/pubmed/19491821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.122
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