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Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has...

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Detaylı Bibliyografya
Yayımlandı:Antiviral Res
Asıl Yazarlar: Zhu, Wenjun, Zhang, Zirui, He, Shihua, Wong, Gary, Banadyga, Logan, Qiu, Xiangguo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844847/
https://ncbi.nlm.nih.gov/pubmed/29369776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.01.011
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