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Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has...

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Bibliografiska uppgifter
I publikationen:Antiviral Res
Huvudupphovsmän: Zhu, Wenjun, Zhang, Zirui, He, Shihua, Wong, Gary, Banadyga, Logan, Qiu, Xiangguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844847/
https://ncbi.nlm.nih.gov/pubmed/29369776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.01.011
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