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Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has...

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Bibliografische gegevens
Gepubliceerd in:Antiviral Res
Hoofdauteurs: Zhu, Wenjun, Zhang, Zirui, He, Shihua, Wong, Gary, Banadyga, Logan, Qiu, Xiangguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844847/
https://ncbi.nlm.nih.gov/pubmed/29369776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.01.011
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