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Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antiviral Res
Auteurs principaux: Zhu, Wenjun, Zhang, Zirui, He, Shihua, Wong, Gary, Banadyga, Logan, Qiu, Xiangguo
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844847/
https://ncbi.nlm.nih.gov/pubmed/29369776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.01.011
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