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Successful treatment of Marburg virus with orally administrated T-705 (Favipiravir) in a mouse model

Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antiviral Res
Hauptverfasser: Zhu, Wenjun, Zhang, Zirui, He, Shihua, Wong, Gary, Banadyga, Logan, Qiu, Xiangguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844847/
https://ncbi.nlm.nih.gov/pubmed/29369776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.01.011
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