Targeting pediatric sarcoma with a bispecific ligand immunotoxin targeting urokinase and epidermal growth factor receptors

Children with high risk sarcoma have a poor prognosis despite surgical resection, irradiation and chemotherapy. Alternative therapies are urgently needed. Urokinase-type plasminogen activator receptor (uPAR) and epidermal growth factor receptor (EGFR) are surface proteins expressed by some pediatric...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pilbeam, Kristy, Wang, Hongbo, Taras, Elizabeth, Bergerson, Rachel J., Ettestad, Brianna, DeFor, Todd, Borgatti, Antonella, Vallera, Daniel A., Verneris, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844719/
https://ncbi.nlm.nih.gov/pubmed/29552283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21187
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