Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes

The development of extracellular vesicles (EV) for therapeutic applications is contingent upon the establishment of reproducible, scalable, and high-throughput methods for the production and purification of clinical grade EV. Methods including ultracentrifugation (U/C), ultrafiltration, immunoprecip...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Watson, Dionysios C., Yung, Bryant C., Bergamaschi, Cristina, Chowdhury, Bhabadeb, Bear, Jenifer, Stellas, Dimitris, Morales-Kastresana, Aizea, Jones, Jennifer C., Felber, Barbara K., Chen, Xiaoyuan, Pavlakis, George N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844027/
https://ncbi.nlm.nih.gov/pubmed/29535850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2018.1442088
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