Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets

Genome studies of diffuse large B-cell lymphoma (DLBCL) have revealed a large number of somatic mutations and structural alterations. However, the clinical significance of these alterations is still not well defined. In this study, we have integrated the analysis of targeted next-generation sequenci...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Karube, K, Enjuanes, A, Dlouhy, I, Jares, P, Martin-Garcia, D, Nadeu, F, Ordóñez, G R, Rovira, J, Clot, G, Royo, C, Navarro, A, Gonzalez-Farre, B, Vaghefi, A, Castellano, G, Rubio-Perez, C, Tamborero, D, Briones, J, Salar, A, Sancho, J M, Mercadal, S, Gonzalez-Barca, E, Escoda, L, Miyoshi, H, Ohshima, K, Miyawaki, K, Kato, K, Akashi, K, Mozos, A, Colomo, L, Alcoceba, M, Valera, A, Carrió, A, Costa, D, Lopez-Bigas, N, Schmitz, R, Staudt, L M, Salaverria, I, López-Guillermo, A, Campo, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843901/
https://ncbi.nlm.nih.gov/pubmed/28804123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.251
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