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Melatonin prevents hypochlorous acid mediated cyanocobalamin destruction and cyanogen chloride generation
Hypochlorous acid (HOCl) is a potent cytotoxic oxidant generated by the enzyme myeloperoxidase (MPO) in the presence of hydrogen peroxide (H(2)O(2)) and chloride (Cl(−)). Elevated levels of HOCl play an important role in various pathological conditions through oxidative modification of several biomo...
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| Veröffentlicht in: | J Pineal Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843513/ https://ncbi.nlm.nih.gov/pubmed/29247550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12463 |
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