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Melatonin prevents hypochlorous acid mediated cyanocobalamin destruction and cyanogen chloride generation

Hypochlorous acid (HOCl) is a potent cytotoxic oxidant generated by the enzyme myeloperoxidase (MPO) in the presence of hydrogen peroxide (H(2)O(2)) and chloride (Cl(−)). Elevated levels of HOCl play an important role in various pathological conditions through oxidative modification of several biomo...

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Bibliografiske detaljer
Udgivet i:J Pineal Res
Main Authors: Jeelani, Roohi, Maitra, Dhiman, Chatzicharalampous, Charalampos, Najeemuddin, Syed, Morris, Robert T., Abu-Soud, Husam M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843513/
https://ncbi.nlm.nih.gov/pubmed/29247550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12463
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