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Relevance of the protein macrodipole in the membrane-binding process. Interactions of fatty-acid binding proteins with cationic lipid membranes

The fatty acid-binding proteins L-BABP and Rep1-NCXSQ bind to anionic lipid membranes by electrostatic interactions. According to Molecular Dynamics (MD) simulations, the interaction of the protein macrodipole with the membrane electric field is a driving force for protein binding and orientation in...

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Publicado en:PLoS One
Main Authors: Galassi, Vanesa V., Villarreal, Marcos A., Montich, Guillermo G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843346/
https://ncbi.nlm.nih.gov/pubmed/29518146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194154
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