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Energetic and entropic contributions to the interactions between like-charged groups in cationic peptides: A molecular dynamics simulation study

The interaction between like-charged amino acid residues has been proposed to stabilize the folded state of peptides and proteins, and to modulate the substrate binding and the action mechanism of enzymes. We have used an alanine- and lysine-based peptide as a model system to study the interaction b...

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Autors principals: Villarreal, Marcos, Montich, Guillermo
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373690/
https://ncbi.nlm.nih.gov/pubmed/12142454
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