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Evaluation of Sorbitol-Methanol Co-Feeding Strategy on Production of Recombinant Human Growth Hormone in Pichia Pastoris

Recombinant protein production in Pichia pastoris is based on alcohol oxidase promoters which are regulated by methanol. However, the use of methanol has several disadvantages, which is why current trends in bioprocess development with Pichia pastoris (P. pastoris) are focusing on methanol mixed fee...

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Bibliografski detalji
Izdano u:Iran J Pharm Res
Glavni autori: Azadi, Saeed, Mahboubi, Arash, Naghdi, Nasser, Solaimanian, Roya, Mortazavi, Seyyed Alireza
Format: Artigo
Jezik:Inglês
Izdano: Shaheed Beheshti University of Medical Sciences 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843317/
https://ncbi.nlm.nih.gov/pubmed/29552064
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