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Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...

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Bibliografische gegevens
Gepubliceerd in:Res Pharm Sci
Hoofdauteurs: Azadi, Saeed, Sadjady, Seyed Kazem, Mortazavi, Seyed Alireza, Naghdi, Nasser, Mahboubi, Arash, Solaimanian, Roya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Medknow Publications & Media Pvt Ltd 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921403/
https://ncbi.nlm.nih.gov/pubmed/29853932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.228953
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