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Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...

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Detalles Bibliográficos
Publicado en:Res Pharm Sci
Main Authors: Azadi, Saeed, Sadjady, Seyed Kazem, Mortazavi, Seyed Alireza, Naghdi, Nasser, Mahboubi, Arash, Solaimanian, Roya
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921403/
https://ncbi.nlm.nih.gov/pubmed/29853932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.228953
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