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Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...

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Библиографические подробности
Опубликовано в: :Res Pharm Sci
Главные авторы: Azadi, Saeed, Sadjady, Seyed Kazem, Mortazavi, Seyed Alireza, Naghdi, Nasser, Mahboubi, Arash, Solaimanian, Roya
Формат: Artigo
Язык:Inglês
Опубликовано: Medknow Publications & Media Pvt Ltd 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921403/
https://ncbi.nlm.nih.gov/pubmed/29853932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.228953
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