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Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Azadi, Saeed, Sadjady, Seyed Kazem, Mortazavi, Seyed Alireza, Naghdi, Nasser, Mahboubi, Arash, Solaimanian, Roya
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921403/
https://ncbi.nlm.nih.gov/pubmed/29853932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.228953
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