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Genotoxicity of ortho-quinones: reactive oxygen species versus covalent modification
o-Quinones are formed metabolically from natural and synthetic estrogens as well as upon exposure to polycyclic aromatic hydrocarbons (PAH) and contribute to estrogen and PAH carcinogenesis by genotoxic mechanisms. These mechanisms include the production of reactive oxygen species to produce DNA str...
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| Published in: | Toxicol Res (Camb) |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Royal Society of Chemistry
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842949/ https://ncbi.nlm.nih.gov/pubmed/29527287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00223h |
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