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Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria
Most of the reported mitochondria targeting molecules are lipophilic and cationic, which may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a well-established protein tag (i.e., FLAG-tag) to...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842676/ https://ncbi.nlm.nih.gov/pubmed/29328651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11582 |
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