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Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria
Most of the reported mitochondria targeting molecules are lipophilic and cationic, which may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a well-established protein tag (i.e., FLAG-tag) to...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842676/ https://ncbi.nlm.nih.gov/pubmed/29328651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11582 |
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