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Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria
Most of the reported mitochondria targeting molecules are lipophilic and cationic, which may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a well-established protein tag (i.e., FLAG-tag) to...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842676/ https://ncbi.nlm.nih.gov/pubmed/29328651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11582 |
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