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Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria

Most of the reported mitochondria targeting molecules are lipophilic and cationic, which may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a well-established protein tag (i.e., FLAG-tag) to...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: He, Hongjian, Wang, Jiaqing, Wang, Huaimin, Zhou, Ning, Yang, Dongsik, Green, Douglas R., Xu, Bing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842676/
https://ncbi.nlm.nih.gov/pubmed/29328651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11582
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