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Involvement of the metabolic sensor GPR81 in cardiovascular control

GPR81 is a receptor for the metabolic intermediate lactate with an established role in regulating adipocyte lipolysis. Potentially novel GPR81 agonists were identified that suppressed fasting plasma free fatty acid levels in rodents and in addition improved insulin sensitivity in mouse models of ins...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wallenius, Kristina, Thalén, Pia, Björkman, Jan-Arne, Johannesson, Petra, Wiseman, John, Böttcher, Gerhard, Fjellström, Ola, Oakes, Nicholas D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841867/
https://ncbi.nlm.nih.gov/pubmed/28978803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92564
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