The PPARα/γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat

Metabolic flexibility was assessed in male Zucker rats: lean controls, obese controls, and obese rats treated with the dual peroxisome proliferator activated receptor (PPAR) α/γ agonist, tesaglitazar, 3 μmol/kg/day for 3 weeks. Whole body glucose disposal rate (R (d)) and hepatic glucose output (HGO...

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Detalhes bibliográficos
Main Authors: Wallenius, Kristina, Kjellstedt, Ann, Thalén, Pia, Löfgren, Lars, Oakes, Nicholas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826326/
https://ncbi.nlm.nih.gov/pubmed/24285952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/305347
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