Diverse cellular architecture of atherosclerotic plaque derives from clonal expansion of a few medial SMCs

Fibrous cap smooth muscle cells (SMCs) protect atherosclerotic lesions from rupturing and causing thrombosis, while other plaque SMCs may have detrimental roles in plaque development. To gain insight into recruitment of different plaque SMCs, we mapped their clonal architecture in aggregation chimer...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Jacobsen, Kevin, Lund, Marie Bek, Shim, Jeong, Gunnersen, Stine, Füchtbauer, Ernst-Martin, Kjolby, Mads, Carramolino, Laura, Bentzon, Jacob Fog
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841865/
https://ncbi.nlm.nih.gov/pubmed/28978793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95890
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