Diverse cellular architecture of atherosclerotic plaque derives from clonal expansion of a few medial SMCs

Fibrous cap smooth muscle cells (SMCs) protect atherosclerotic lesions from rupturing and causing thrombosis, while other plaque SMCs may have detrimental roles in plaque development. To gain insight into recruitment of different plaque SMCs, we mapped their clonal architecture in aggregation chimer...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Jacobsen, Kevin, Lund, Marie Bek, Shim, Jeong, Gunnersen, Stine, Füchtbauer, Ernst-Martin, Kjolby, Mads, Carramolino, Laura, Bentzon, Jacob Fog
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841865/
https://ncbi.nlm.nih.gov/pubmed/28978793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95890
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