Comparison of neuroprotective efficacy of poly-arginine R18 and R18D (D-enantiomer) peptides following permanent middle cerebral artery occlusion in the Wistar rat and in vitro toxicity studies

We have previously demonstrated that arginine-rich and poly-arginine peptides possess potent neuroprotective properties, with poly-arginine peptide R18 identified as being highly effective at reducing infarct volume following middle cerebral artery occlusion (MCAO) in the Sprague Dawley rat. Since p...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Milani, Diego, Bakeberg, Megan C., Cross, Jane L., Clark, Vince W., Anderton, Ryan S., Blacker, David J., Knuckey, Neville W., Meloni, Bruno P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841795/
https://ncbi.nlm.nih.gov/pubmed/29513757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193884
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