Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model

BACKGROUND: We recently reported that poly-arginine peptides have neuroprotective properties both in vitro and in vivo. In cultured cortical neurons exposed to glutamic acid excitotoxicity, we demonstrated that neuroprotective potency increases with polymer length plateauing at R15 to R18 (R = argin...

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Vydáno v:BMC Neurosci
Hlavní autoři: Milani, Diego, Clark, Vince W., Cross, Jane L., Anderton, Ryan S., Knuckey, Neville W., Meloni, Bruno P.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855717/
https://ncbi.nlm.nih.gov/pubmed/27142074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0253-z
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