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Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model

BACKGROUND: We recently reported that poly-arginine peptides have neuroprotective properties both in vitro and in vivo. In cultured cortical neurons exposed to glutamic acid excitotoxicity, we demonstrated that neuroprotective potency increases with polymer length plateauing at R15 to R18 (R = argin...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Milani, Diego, Clark, Vince W., Cross, Jane L., Anderton, Ryan S., Knuckey, Neville W., Meloni, Bruno P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855717/
https://ncbi.nlm.nih.gov/pubmed/27142074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0253-z
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