Poly-arginine R18 and R18D (D-enantiomer) peptides reduce infarct volume and improves behavioural outcomes following perinatal hypoxic-ischaemic encephalopathy in the P7 rat

We examined the neuroprotective efficacy of the poly-arginine peptide R18 and its D-enantiomer R18D in a perinatal hypoxic-ischaemic (HI) model in P7 Sprague-Dawley rats. R18 and R18D peptides were administered intraperitoneally at doses of 30, 100, 300 or 1000 nmol/kg immediately after HI (8% O(2)/...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Edwards, Adam B., Cross, Jane L., Anderton, Ryan S., Knuckey, Neville W., Meloni, Bruno P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810179/
https://ncbi.nlm.nih.gov/pubmed/29426351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0352-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados