Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial

Background: By the early 1980s, tuberculosis treatment was shortened from 24 to 6 months, maintaining relapse rates of 1-2%. Subsequent trials attempting shorter durations have failed, with 4-month arms consistently having relapse rates of 15-20%. One trial shortened treatment only among those witho...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Gates Open Res
Hlavní autoři: Chen, Ray Y., Via, Laura E., Dodd, Lori E., Walzl, Gerhard, Malherbe, Stephanus T., Loxton, André G., Dawson, Rodney, Wilkinson, Robert J., Thienemann, Friedrich, Tameris, Michele, Hatherill, Mark, Diacon, Andreas H., Liu, Xin, Xing, Jin, Jin, Xiaowei, Ma, Zhenya, Pan, Shouguo, Zhang, Guolong, Gao, Qian, Jiang, Qi, Zhu, Hong, Liang, Lili, Duan, Hongfei, Song, Taeksun, Alland, David, Tartakovsky, Michael, Rosenthal, Alex, Whalen, Christopher, Duvenhage, Michael, Cai, Ying, Goldfeder, Lisa C., Arora, Kriti, Smith, Bronwyn, Winter, Jill, Barry III, Clifton E.
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000 Research Limited 2017
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841574/
https://ncbi.nlm.nih.gov/pubmed/29528048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/gatesopenres.12750.1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky