Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial

Background: By the early 1980s, tuberculosis treatment was shortened from 24 to 6 months, maintaining relapse rates of 1-2%. Subsequent trials attempting shorter durations have failed, with 4-month arms consistently having relapse rates of 15-20%. One trial shortened treatment only among those witho...

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Bibliografiska uppgifter
I publikationen:Gates Open Res
Huvudupphovsmän: Chen, Ray Y., Via, Laura E., Dodd, Lori E., Walzl, Gerhard, Malherbe, Stephanus T., Loxton, André G., Dawson, Rodney, Wilkinson, Robert J., Thienemann, Friedrich, Tameris, Michele, Hatherill, Mark, Diacon, Andreas H., Liu, Xin, Xing, Jin, Jin, Xiaowei, Ma, Zhenya, Pan, Shouguo, Zhang, Guolong, Gao, Qian, Jiang, Qi, Zhu, Hong, Liang, Lili, Duan, Hongfei, Song, Taeksun, Alland, David, Tartakovsky, Michael, Rosenthal, Alex, Whalen, Christopher, Duvenhage, Michael, Cai, Ying, Goldfeder, Lisa C., Arora, Kriti, Smith, Bronwyn, Winter, Jill, Barry III, Clifton E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: F1000 Research Limited 2017
Ämnen:
Study Protocol
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841574/
https://ncbi.nlm.nih.gov/pubmed/29528048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/gatesopenres.12750.1
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