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Insights into the impact of a membrane-anchoring moiety on the biological activities of bivalent compounds as potential neuroprotectants for Alzheimer’s disease

Bivalent compounds anchoring in different manners to the membrane were designed and biologically characterized to understand the contribution of the anchor moiety to their biological activity as neuroprotectants for Alzheimer’s disease. Our results established that the anchor moiety is essential and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Med Chem
मुख्य लेखकों: He, Liu, Jiang, Yuqi, Liu, Kai, Gomez-Murcia, Victoria, Ma, Xiaopin, Torrecillas, Alejandro, Chen, Qun, Zhu, Xiongwei, Lesnefsky, Edward, Gomez-Fernandez, Juan C., Xu, Bin, Zhang, Shijun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841544/
https://ncbi.nlm.nih.gov/pubmed/29271648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b01284
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