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PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer
The anti-apoptotic nature of cancer cells often impedes the effects of anti-cancer therapeutic agents. Multiple death signals influence mitochondria during apoptosis, and though many studies have attempted to elucidate these complicated pathways, Bax oligomerization, an important step in the process...
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Foilsithe in: | Cell Death Discov |
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Main Authors: | , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Nature Publishing Group UK
2018
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841295/ https://ncbi.nlm.nih.gov/pubmed/29531808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0006-5 |
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