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A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis
Calcific aortic valve stenosis (CAVS) is a common and life-threatening heart disease and the current treatment options cannot stop or delay its progression. A GWAS on 1009 cases and 1017 ethnically matched controls was combined with a large-scale eQTL mapping study of human aortic valve tissues (n =...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840407/ https://ncbi.nlm.nih.gov/pubmed/29511167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03260-6 |
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