Aortic valve-specific genes dysregulated in calcific aortic valve stenosis as potential biomarkers and therapeutic targets

Summary: Calcific aortic valve stenosis (CAVS) is the most frequent heart valve disease. Elucidating specific gene expression patterns in the aortic valve could provide new insights for understanding disease pathophysiology. We used local RNA sequencing data from 500 explanted human aortic valves to...

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Autors principals:	Pardis Zamani, Ursula Houessou, Hasanga D. Manikpurage, Zhonglin Li, Manel Dahmene, Nathalie Gaudreault, François Dagenais, Marie-Annick Clavel, Philippe Pibarot, Benoit J. Arsenault, Patrick Mathieu, Yohan Bossé, Sébastien Thériault
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-07-01
Col·lecció:	HGG Advances
Matèries:	calcific aortic valve stenosis transcriptomics biomarkers gene expression plasma proteins
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S266624772500051X
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