A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

Calcific aortic valve stenosis (CAVS) is a common and life-threatening heart disease and the current treatment options cannot stop or delay its progression. A GWAS on 1009 cases and 1017 ethnically matched controls was combined with a large-scale eQTL mapping study of human aortic valve tissues (n =...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Thériault, Sébastien, Gaudreault, Nathalie, Lamontagne, Maxime, Rosa, Mickael, Boulanger, Marie-Chloé, Messika-Zeitoun, David, Clavel, Marie-Annick, Capoulade, Romain, Dagenais, François, Pibarot, Philippe, Mathieu, Patrick, Bossé, Yohan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840407/
https://ncbi.nlm.nih.gov/pubmed/29511167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03260-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items