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Increased Glutamine Consumption in Cisplatin-Resistant Cells Has a Negative Impact on Cell Growth

The emergence of drug-resistant subclones remains the primary reason for tumor treatment failure. Some theories suggest that drug-resistant cell growth can be suppressed by drug-sensitive cells because resistant cells are less fit than sensitive cells in the absence of drug. We investigated fitness...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Duan, Guihua, Shi, Mengyue, Xie, Lijuan, Xu, Mingcui, Wang, Yun, Yan, Hongli, Zhuge, Yuzheng, Zou, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840399/
https://ncbi.nlm.nih.gov/pubmed/29511244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21831-x
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