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Increased Glutamine Consumption in Cisplatin-Resistant Cells Has a Negative Impact on Cell Growth

The emergence of drug-resistant subclones remains the primary reason for tumor treatment failure. Some theories suggest that drug-resistant cell growth can be suppressed by drug-sensitive cells because resistant cells are less fit than sensitive cells in the absence of drug. We investigated fitness...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Duan, Guihua, Shi, Mengyue, Xie, Lijuan, Xu, Mingcui, Wang, Yun, Yan, Hongli, Zhuge, Yuzheng, Zou, Xiaoping
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840399/
https://ncbi.nlm.nih.gov/pubmed/29511244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21831-x
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