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Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody
Oligosaccharides are generally considered to be un-utilized for growth of mammalian cells because their permeability across the cell membrane is low. However, in our previous study, we discovered that CHO and HEK293 cells consume maltose in culture media without serum and glucose. This is interestin...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840386/ https://ncbi.nlm.nih.gov/pubmed/29511312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22490-8 |
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