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Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos

Embryonic development is initially controlled by maternal RNAs and proteins stored in the oocyte, until gene products gradually generated by the embryo itself take over. Major embryonic genome activation (EGA) in bovine embryos occurs at the eight- to 16-cell stage. Morphological observations, such...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lavagi, Ilaria, Krebs, Stefan, Simmet, Kilian, Beck, Andrea, Zakhartchenko, Valeri, Wolf, Eckhard, Blum, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840315/
https://ncbi.nlm.nih.gov/pubmed/29511234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22248-2
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