Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos

Embryonic development is initially controlled by maternal RNAs and proteins stored in the oocyte, until gene products gradually generated by the embryo itself take over. Major embryonic genome activation (EGA) in bovine embryos occurs at the eight- to 16-cell stage. Morphological observations, such...

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Vydáno v:Sci Rep
Hlavní autoři: Lavagi, Ilaria, Krebs, Stefan, Simmet, Kilian, Beck, Andrea, Zakhartchenko, Valeri, Wolf, Eckhard, Blum, Helmut
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840315/
https://ncbi.nlm.nih.gov/pubmed/29511234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22248-2
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