OCT4/POU5F1 is required for NANOG expression in bovine blastocysts

Mammalian preimplantation development involves two lineage specifications: first, the CDX2-expressing trophectoderm (TE) and a pluripotent inner cell mass (ICM) are separated during blastocyst formation. Second, the pluripotent epiblast (EPI; expressing NANOG) and the differentiated primitive endode...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Simmet, Kilian, Zakhartchenko, Valeri, Philippou-Massier, Julia, Blum, Helmut, Klymiuk, Nikolai, Wolf, Eckhard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856541/
https://ncbi.nlm.nih.gov/pubmed/29483258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718833115
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