Differential Phagocytic Properties of CD45(low) Microglia and CD45(high) Brain Mononuclear Phagocytes—Activation and Age-Related Effects

In the central nervous system (CNS), microglia are innate immune mononuclear phagocytes (CNS MPs) that can phagocytose infectious particles, apoptotic cells, neurons, and pathological protein aggregates, such as Aβ in Alzheimer’s disease (AD). While CD11b(+)CD45(low) microglia account for the majori...

Full description

Saved in:
Bibliographic Details
Published in:Front Immunol
Main Authors: Rangaraju, Srikant, Raza, Syed Ali, Li, Noel Xiang’An, Betarbet, Ranjita, Dammer, Eric B., Duong, Duc, Lah, James J., Seyfried, Nicholas T., Levey, Allan I.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840283/
https://ncbi.nlm.nih.gov/pubmed/29552013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00405
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items