Structure-Activity Relationship Analysis of 3-Phenylcoumarin-Based Monoamine Oxidase B Inhibitors

Monoamine oxidase B (MAO-B) catalyzes deamination of monoamines such as neurotransmitters dopamine and norepinephrine. Accordingly, small-molecule MAO-B inhibitors potentially alleviate the symptoms of dopamine-linked neuropathologies such as depression or Parkinson's disease. Coumarin with a f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Chem
मुख्य लेखकों: Rauhamäki, Sanna, Postila, Pekka A., Niinivehmas, Sanna, Kortet, Sami, Schildt, Emmi, Pasanen, Mira, Manivannan, Elangovan, Ahinko, Mira, Koskimies, Pasi, Nyberg, Niina, Huuskonen, Pasi, Multamäki, Elina, Pasanen, Markku, Juvonen, Risto O., Raunio, Hannu, Huuskonen, Juhani, Pentikäinen, Olli T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2018
विषय:
Chemistry
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840146/
https://ncbi.nlm.nih.gov/pubmed/29552556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00041
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