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Many helper T cell subsets have Fas ligand-dependent cytotoxic potential
CD4(+) helper T cells can have cytotoxic activity against cells displaying relevant peptide-MHCII (p:MHCII) ligands. Cytotoxicity may be a property of Th1 cells and depend on perforin and the Eomes transcription factor. We assessed these assertions for polyclonal p:MHCII-specific CD4(+) T cells acti...
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| 發表在: | J Immunol |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840022/ https://ncbi.nlm.nih.gov/pubmed/29436413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700420 |
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