Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Nuclear receptors regulate gene expression in response to environmental cues, but the molecular events governing the cell-type specificity of nuclear receptors remain poorly understood. Here we outline a role for a non-coding RNA in modulating the cell type-specific actions of LXRs, sterol-activated...

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Udgivet i:Nat Med
Main Authors: Sallam, Tamer, Jones, Marius, Thomas, Brandon J, Wu, Xiaohui, Gilliland, Thomas, Qian, Kevin, Eskin, Ascia, Casero, David, Zhang, Zhengyi, Sandhu, Jaspreet, Salisbury, David, Rajbhandari, Prashant, Civelek, Mete, Hong, Cynthia, Ito, Ayaka, Liu, Xin, Daniel, Bence, Lusis, Aldons J, Whitelegge, Julian, Nagy, Laszlo, Castrillo, Antonio, Smale, Stephen, Tontonoz, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839972/
https://ncbi.nlm.nih.gov/pubmed/29431742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4479
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