Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Nuclear receptors regulate gene expression in response to environmental cues, but the molecular events governing the cell-type specificity of nuclear receptors remain poorly understood. Here we outline a role for a non-coding RNA in modulating the cell type-specific actions of LXRs, sterol-activated...

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Publicat a:Nat Med
Autors principals: Sallam, Tamer, Jones, Marius, Thomas, Brandon J, Wu, Xiaohui, Gilliland, Thomas, Qian, Kevin, Eskin, Ascia, Casero, David, Zhang, Zhengyi, Sandhu, Jaspreet, Salisbury, David, Rajbhandari, Prashant, Civelek, Mete, Hong, Cynthia, Ito, Ayaka, Liu, Xin, Daniel, Bence, Lusis, Aldons J, Whitelegge, Julian, Nagy, Laszlo, Castrillo, Antonio, Smale, Stephen, Tontonoz, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839972/
https://ncbi.nlm.nih.gov/pubmed/29431742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4479
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