Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Host-protective caspase-1 activity must be tightly regulated to prevent pathology, but mechanisms controlling the duration of cellular caspase-1 activity are unknown. Caspase-1 is activated on inflammasomes, signaling platforms that facilitate caspase-1 dimerization and autoprocessing. Previous stud...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Boucher, Dave, Monteleone, Mercedes, Coll, Rebecca C., Chen, Kaiwen W., Ross, Connie M., Teo, Jessica L., Gomez, Guillermo A., Holley, Caroline L., Bierschenk, Damien, Stacey, Katryn J., Yap, Alpha S., Bezbradica, Jelena S., Schroder, Kate
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839769/
https://ncbi.nlm.nih.gov/pubmed/29432122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172222
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker