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Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals

Inflammation is the host response to microbial infection or sterile injury that aims to eliminate the insult, repair the tissue and restore homeostasis. Macrophages and the NLRP3 inflammasome are key sentinels for both types of insult. Although it is well established that the NLRP3 inflammasome is a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Mol Immunol
Päätekijät: Bezbradica, Jelena S, Coll, Rebecca C, Schroder, Kate
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214936/
https://ncbi.nlm.nih.gov/pubmed/26996064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.11
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